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PHYSICAL PROPERTIES OF ACTIVE PHARMACEUTICAL INGREDIENT

Active Pharmaceutical Ingredient

The physical behaviour or rather characteristics of an active pharmaceutical ingredient plays a very crucial role towards its suitability for use.

This factor is very critical because in one way or another, it will have an impact on the ability to manufacture the medicine. For the dosage to be in its ultimate form, the flow properties of the active pharmaceutical ingredient must enable easy conveying, handling and also mixing.

The physical property of an active pharmaceutical ingredient also affects the rate of absorption of the drug in question. This can be directly linked to solubilisation capacity of the API, an aspect which is very important in determining the rate at which the drug is absorbed into the body system.

When you visit a health centre, the type of dosage the medical practitioner will choose for your treatment will entirely depend many different factors which are interlinked.

Some of this factors are portability and acceptability by the patient, therapeutic use of the compound and the nature of the active pharmaceutical ingredient (either chemical nature or physical nature).

Extensive studies have shown that about 90% of all medicines are solid in nature. This therefore has characterized the active pharmaceutical ingredients as very important, more so when its actual solubility is ultimately low!

When comparing the physical properties of APIs, it was realized that the properties of active pharmaceutical ingredient to be used in coming up with liquid and semi-solid dosages are not of much importance as those used in solid dosages, unless the solubility of the API is affected greatly.

According to the information above, we can learn than the physical properties of these ingredients play a positive role in the making of different types of dosages. Besides the physical properties, we also have the chemical properties and microbiological properties of the same.

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